Technical Condition Optimization of Semi-bionic Extraction for Kanggan Liyan Syrups by Uniform Design
- VernacularTitle:均匀设计法优选抗感利咽糖浆半仿生法提取的工艺条件
- Author:
Yang YANG
;
Liangyong HUANG
;
Shiming DU
;
Guangyi YANG
- Publication Type:Journal Article
- Keywords:
Uniform design;
Kanggan Liyan syrups;
Semi-bionic extraction;
Technical condition
- From:
China Pharmacist
2015;(1):49-51,82
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the conditions of semi-bionic extraction for Kanggan Liyan syrups. Methods: The samples were extracted by water with different pH values under the same conditions of formula composition and dosage, extraction temperature, filtration method, water voulme, centrifugal time and concentration multiple. The best conditions of the semi-bionic extraction for Kang-gan Liyan syrups were screened by uniform design with the content of forsythoside A, polydatin, baicalin and emodin and the dried ex-tract weight as the indices. Results:The best technical conditions were as follows:the pH value of water for the 1st, 2nd and 3rd de-coction was 4. 9, 7. 5 and 9. 0, respectively, and the total extraction time was 2h. Conclusion:According to the industrial production conditions, the pH value of water for the 1st, 2nd and 3rd decoction is 5. 0, 7. 5 and 9. 0 with the extraction time of 1h,0. 5h and 0. 5h, respectively.