Rationality Analysis of Prophylactic Application of Antibiotics during Perioperative Period in Patients with Type Ⅱ Incision Operation in Gynecology and Obstetrics before and after Intervention
- VernacularTitle:干预前后妇产科Ⅱ类切口手术围手术期预防应用抗菌药合理性分析
- Author:
Yanping HU
;
Yuan ZHANG
;
Hongyan QIAN
- Publication Type:Journal Article
- Keywords:
Antibiotics;
Obstetrics and gynecology;
Type Ⅱ incision operation;
Prophylaxis;
Intervention
- From:
China Pharmacist
2015;(2):258-259,260
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the rationality of prophylactic antibiotics application during perioperative period in the pa-tients with type Ⅱ incision operation in gynecology and obstetrics in our hospital after the intervention. Methods:Totally 274 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2012 to March 2013 were collect-ed as the control group, another 321 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2013 to March 2014 were collected as the intervention group. The rationality of prophylactic antibiotics application before and after the intervention was compared. Results:Compared with those in the control group, the average administration time, the hos-pitalization time and the cost of antimicrobial agents were significantly decreased in the intervention group (P<0. 05). The incidence of adverse drug reactions and operation incision infection between the two groups was not significant difference (P>0. 05). Compared with those in the control group, the incidence of irrational choice of antibacterial drugs, the combined use without indication, irrational medication time,over-time use, inappropriate use and improper choice of solvents in the intervention group was significantly reduced ( P<0. 05). Conclusion:After the intervention, the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital is improved significantly.