Effects of Alkalinized Lidocaine with Endotracheal Intubation Intracuff Injection on Occurrence of Cough and Sore Throat in Smoking Patients after Operation
- VernacularTitle:气管内插管套囊内注入碱化利多卡因对吸烟患者术后咽喉疼、呛咳的影响
- Author:
Guannan XIE
;
Xiujuan GAO
- Publication Type:Journal Article
- Keywords:
Endotracheal intubation;
Lidocaine;
Cough;
Sore throat;
Smoking patients
- From:
China Pharmacist
2015;(3):437-438,448
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of alkalinized lidocaine with endotracheal intubation intracuff injection on the occur-rence of cough and sore throat in the smoking patients after operation. Methods:A prospective and double-blind trial was carried out. Totally 50 smoking patients undergoing surgery under general anesthesia were enrolled. The patients were randomly allocated to receive either ETT intracuff injection of alkalinized 2% lidocaine (group L) or ETT intracuff injection of 0. 9% saline (group S). The inci-dence of cough and sore throat in the two groups was compared. The duration of anesthesia and the time between anesthesia termination and extubation were also recorded. Results:Group L was superior to group S in reducing cough (P<0. 001). The incidence of postop-erative sore throat in group L was significantly lower than that in group S in the post-anesthesia care unit (PACU) (P<0. 05). How-ever, the incidence of sore throat was not significantly different in the two groups at 24h after the extubation (P>0. 05). Conclusion:The intracuff injection of alkalinized lidocaine is superior to saline in decreasing the incidence of postoperative cough and sore throat in smoking patients.
