Expressions of CD44v3 and CD54 in oral premalignant epithelia
- VernacularTitle:CD44v3和CD54在口腔黏膜癌变中的表达
- Author:
Yuan LI
;
Jinzhong LIU
;
Yanli ZHENG
- Publication Type:Journal Article
- Keywords:
Oral cancer;
Dysplastic epithelia;
CD44v3;
CD54
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expressions of CD44v3 and CD54 in oral premalignant epithelia and its significance in the carcinogenesis of oral mucosa.Methods:The expressions of CD44v3 and CD54 in 19 cases of normal mucosa and mucosal hyperplasia,22 case of dysplastic epithelia,26 cases of oral cancer mucosa were detected by using immunohistochemistry.Results:CD44v3 and CD54 proteins showed no expression or micro-expression in normal and hyperplastic epithelia.The expressions increased in the dysplastic epithelia and mucosa of oral cancer gradually.The difference between the expressions of the three groups was significant(P
