Semiquantitative RT-PCR analysis of apoptotic protease activating factor 1 in oral squamous cell carcinoma
- VernacularTitle:半定量PCR检测口腔鳞状细胞癌凋亡蛋白酶活化因子的表达
- Author:
Chunyan LI
;
Wenxin GAO
;
Ruhui ZHANG
;
Lin WANG
;
Jinghui ZHAO
;
Yanqiu LI
- Publication Type:Journal Article
- Keywords:
Apoptotic protease activating factor 1;
Oral squamous cell carcinoma;
Gene expression;
Semiquantitative RT-PCR
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between apoptotic protease activating factor 1(APAF1) gene and oral squamous cell carcinoma (OSCC). Methods:The mRNA expression of APAF1 gene were detected with semiquantitative RT-PCR method in 18 cases of normal oral mucous membrane and 32 cases of OSCC tissues. Results:The expression of APAF1 gene was significantly decreased in OSCC tissues comparing with the normal oral mucous membrane(P