The vitro bioactivity of new titanium alloy modified by anodic oxidation and its effects on osteoblast-like adhesion
- VernacularTitle:阳极氧化处理后的新型钛合金体外诱导实验及对成骨细胞早期附着的影响
- Author:
Xue HAN
;
Jiuyu SONG
;
Zequan HUA
- Publication Type:Journal Article
- Keywords:
Biomedical titanium alloy;
Anodic oxidation;
MG63 cell;
Adhesion
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the vitro bioactivity of the Ti-24Nb-4Zr-7.9Sn (TNZS) disks modified by anodic oxidation(AD) and its effects on adhesion of human osteoblast-like MG63 cells. Methods:The TNZS titanium alloy disks were treated with anodic oxidation and the bioactivity was assessed by investigating the formation of apatite on the film surface after soaking in simulated body fluids. The surface composition of the specimens after immersion was evaluated by EDX and X-ray diffraction. MG63 osteoblast-like cells were seeded on the Ti6Al4V,TNZS,AD-TNZS disks, and then the number of attached cells were counted and the cell morphology was examined at each given period. Results:The apatite can form on the treated TNZS disks after soaking in SBF for 6 days. The ratio of attached MG63 on AD-TNZS disks after 60 or 120 min seeding were significant higher than that on other samples and the cells on AD-TNZS disks spread better. Conclusion:The TNZS alloy modified by anodic oxidation can induce apatite formation in SBF and increase the early attachment of osteoblasts.
