Expression of pituritary tumor transforming gene and basic fibroblast growth factor in oral squamous cell carcinoma and related clinical importance
- VernacularTitle:PTTG和bFGF在口腔鳞癌中的表达及意义
- Author:
Yumei DING
;
Handong ZHANG
- Publication Type:Journal Article
- Keywords:
Mouth;
Squamous cell carcinoma;
PTTG;
bFGF;
Immunohistochemistry
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression of pituitary tumor transforming gene (PTTG) and basic fibroblast growth factor (bFGF) in oral squamous cell carcinoma and their relation with each other, as well as the relationship of their expression with clinical-pathological indexes. Methods: The expression of PTTG and bFGF were examined among 55 oral squamous cell carcinoma tissues and 10 normal oral mucosal tissues by the streptavidin-biotinperoxidase (S-P) method. Results:The positive rate of PTTG and bFGF was 78.2% and 67.3% respectively in oral squamous cell carcinoma. The positive rate and grade of PTTG and bFGF were significantly higher than that in the normal mucosa tissues (P
