Effects of the static compressive stress on the proliferation and apoptosis of condylar chondrocytes in vitro
- VernacularTitle:不同静压力对新生SD大鼠髁突软骨细胞增殖与凋亡的影响
- Author:
Song LI
;
Weihua GUO
;
Yun XU
- Publication Type:Journal Article
- Keywords:
Mandibular condylar chondrocytes;
Compressive stress;
Apoptosis
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of the different static compressive stress on the proliferation and apoptosis of condylar chondrocytes in vitro.Methods: 0, 12, 24, 36 kPa static compressive stress were applied to the third passage of mandibular condylar chondrocytes for 1 hour respectively. The changes of proliferation and apoptosis of condylar chondrocytes were evaluated by flow cytometry analysis. Results: The index of proliferation and apoptosis of cells decreased with the magnitude value of static compressive stress except 24 kPa group. The most significant decrease of proliferative index and apoptosis index was found in 36 kPa group and 12 kPa group respectively. Conclusion: There might be some corelationships between magnitude of static compressive stress and the proliferation and apoptosis of condylar chondrocytes.
