Correlation between expression of vascular cell adhesion molecule-1 and macrophage infiltration in human oral squamous cell carcinoma
- VernacularTitle:口腔鳞癌中血管细胞黏附分子-1的表达与巨噬细胞浸润的关系
- Author:
Legang SUN
;
Ling LIU
;
Yufeng SONG
- Publication Type:Journal Article
- Keywords:
Oral squamous cell carcinoma;
VCAM-1;
Macrophage;
Infiltration
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the role of vascular cell adhesion molecule-1(VCAM-1)on macrophage infiltration and recruitment in oral squamous cell carcinoma(OSCC). Methods:After detecting the expression of VCAM-1 and macrophage infiltration in OSCC by immunohistochemistry, light microscope was used for counting macrophages. Results:The expression level of VCAM-1 (64.58%)and macrophage numbers(81.04?12.00) was significantly higher in OSCC than those in normal oral mucosa. The expression of VCAM-1 in OSCC was not only related to the tumor infiltration and metastasis in OSCC(P
