Variation of iNOS expression in periodontal tissues of rats with periodontitis in orthodontic tooth movement
- VernacularTitle:牙周炎大鼠正畸牙齿移动中牙周组织内iNOS的表达变化
- Author:
Baoyong LI
;
Yin DING
;
Feng PAN
- Publication Type:Journal Article
- Keywords:
Inducible nitric oxide synthase(iNOS);
Nitric oxide(NO);
Orthodontic tooth movement;
Periodontitis
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the changes of iNOS expression in periodontal tissues of rats with periodontitis in orthodontic tooth movement. Methods:48 SD rats at 10 weeks were divided randomly into two groups: periodontitis teeth group and normal teeth group. The maxillary first molar was pulled mesially both in the two groups. 4 rats were executed each time after activation of pull-spring 1, 2, 3, 7,14 and 21d both in two groups. iNOS immunohistochemistry staining were done to compare the expression variations. Results: There were significant differences between the two groups in 2,3, 7, 14 and 21 d. The periodontitis teeth group had stronger positive signals. Conclusion: Periodontitis will increase the expression of iNOS in the rats periodontal tissue during tooth movement, and influence the reconstruction of periodontium.
