The effects of human parathyroid hormone 1-34 on the development and mineralization of rats' dentin
- VernacularTitle:人甲状旁腺激素1-34对大鼠牙本质形成和矿化的影响
- Author:
Xinmei CHEN
;
Yu SUN
;
Hong TAN
- Publication Type:Journal Article
- Keywords:
Human Parathyroid hormone 1-34;
Parathyroidectomy;
Dentin;
Development and mineralization
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of parathyroid hormone(PTH) upon dentinogenesis by investigating the effects of hPTH1-34 on the development and calcification of parathyroidectomy rats' dentin. Methods: hPTH1-34 were injected into SD rats at different dosages after parathyroidectomy. Six weeks later lower incisors were dissected and prepared for light microscopy and image analysis. Results:The concentration of serum calcium decreased after parathyroidectomy, while increased after being injected hPTH1-34. The results of light microscopy and image analysis revealed the enlargement of the predentinal tubules and the presence of mineralization defects in the PTX group(P
