The optimized condition for delivery gtfB antisense oligonucleotide into Streptococcus mutans
- VernacularTitle:寡核苷酸转化变形链球菌方法的筛选
- Author:
Gang XIAO
;
Qingyu GUO
;
Rui LI
- Publication Type:Journal Article
- Keywords:
Streptococcus mutans;
Antisense oligodeoxyribonucleotide;
Transformation;
Dental caries
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Conclusion:So-fastTM can greatly improve the penetration of PS-ODN into S.mutans and can be used as appropriate delivery system of PS-ODN for S.mutans. No matter what approaches were adopted, the uptake rate reached the maximum at 5 ?mol/L and 2 h-exposure. The penetration can not be enhanced by increasing the PS-ODN concentration and the transformation time.