COX-2 and bFGF expression in the development of oral squamous cell carcinoma
- VernacularTitle:COX-2、bFGF在口腔鳞癌发生发展过程中的表达及相互关系
- Author:
Junjie WANG
;
Yuyan LIU
;
Wenxin GAO
- Publication Type:Journal Article
- Keywords:
Cyclooxygenase-2;
Basic fibroblast growth factors;
Oral;
Squamous cell carcinome;
Immunohistochemistry techniques
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To study the role of COX-2 and bFGF in the development of oral squamous cell carcinoma(OSCC).Methods:The expressions of COX-2 and bFGF were exmined by immunohistochemical staining with anti-COX-2 and anti-bFGF monoclonal antibodies respectively in 23 cases of OSCC,25 of oral leukoplakia(OLK)and 10 of normal oral mucosa.Results:COX-2 was detected in 20/23 cases of OSCC,13/25 of OLK and 0/10 of normal oral mucosa(P
