Nucleotide polymorphisms analysis of dentin sialoprotein
- VernacularTitle:DSP基因编码区序列的多态性研究
- Author:
Ying WANG
;
Ying ZHANG
;
Junnan SHI
- Publication Type:Journal Article
- Keywords:
Dentin sialoprotein;
Single nucleotide polymorphism (SNP)
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyse the nucleotide polymorphism of dentin sialoprotein(DSP) coden region in Chinese people. Methods:The DSP segments were amplified by PCR;single-stranded conformation polymorphism(SSCP) and DNA sequencing were employed to detect the nucleotide polymorphisms in DSP coden region. Results:Three single nucleotide polymorphisms(SNP) were found in DSP coden region,two were same sense SNPs resulting in no change of amino acid product,and one was missense SNP resulting in change of asparagine and aspartic acid. Conclusion:There are some SNPs existing in DSP coden region in Chinese people.
