The effects of parathyroid hormone on BMP3 expression of cultured human dental papilla mesenchymal cells
- VernacularTitle:甲状旁腺激素对人牙乳头间充质细胞骨形成蛋白3表达的影响
- Author:
Xinmei CHEN
;
Mingzhen XIAO
;
Lianjia YANG
;
Longxing NI
- Publication Type:Journal Article
- Keywords:
Parathyroid hormone;
BMP;
Dental papilla cells
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of parathyroid hormone (PTH) on BMP3 expression of cultured human dental papilla mesenchymal cells (DPMCs). Methods:DPMCs were obtained by cell culture, BMP3 mRNA expression was studied by in situ hybridization. BMP3 gene expression of human DPMCs after exposure to 33.3 nmol/L PTH for 5 days were measured. The cells cultured in the medium without PTH served as control.Results: Stronger BMP3 positive signals were observed in PTH treated cells than that in the control cells.Conclusion:PTH stimulats BMP3 systhesis of cultured DPMCs.
