Expression of platelet-derived growth factor receptor in periapical granuloma
- VernacularTitle:血小板衍化生长因子受体在人根尖周肉芽组织中表达的意义
- Author:
Qiang CHEN
;
Junnan SHI
;
Yan JIN
;
Yu ZHAO
- Publication Type:Journal Article
- Keywords:
Platelet-derived growth factorreceptor;
Periapical granuloma;
Immunohistochemistry
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression of platelet-derived growth factor receptor (PDGF-R) in periapical granuloma.Methods:Immunohistochemical staining was conducted on prepared specimens of 15 cases of human periapical granuloma. Results:The expression of PDGF receptor ? was detected in fibroblasts,capillary endothelial cells,plasmacytes and macrophage cells in all the 15 cases of human periapical granuloma.Conclusion:These results suggested that these cells are the target cells of PDGF, and PDGF may play an important role in the lesion.