CSF-1 and TGF-?1 Expression in periodontal tissue of third premolar germ during second primary molar orthodontic movement in dog.
- VernacularTitle:正畸移动狗乳磨牙后其恒牙胚牙周组织CSF-1及TGF-?1的表达及意义
- Author:
Zuolin JIN
;
Zhu LIN
;
Guanghai JIAO
- Publication Type:Journal Article
- Keywords:
Deciduous tooth;
Orthodontic;
Permanent tooth;
Tooth germ;
Colony-stimulatius facfors;
Trans forming growth facfors;
Immunohistochemical technique
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression of CSF-1 and TGF-?1 in periodontal tissue of third premolar germ during second primary molar orthodontic movement in dog. Methods: Orthodontic appliance with the force of 0.784 N for the mesial movement of mandible second primary molar was used in 4 dogs for 14 d.Then the samples including mandibular second and third molars and surrounding tissues were prepared for CSF-1 and TGF-?1 detection by immunohistochemical staining technique. Results: Strong CSF-1, TGF-?1 expression was found in the dental follicle and alveolar bone of mesial part of third premolar germ, and weak in the dental follicle and alveolar bone of distal part of third premolar germ in the treated side of the dogs. Conclusion: CSF-1 and TGF-?1 may play roles in the bone remodeling for orthodontic primary tooth movement.