Immunohistochemical localization of dental matrix protein 1 in carious human permanent teeth
- VernacularTitle:牙本质基质蛋白1在人不同龋坏牙齿中的免疫定位
- Author:
Jianliang PANG
;
Buling WU
;
Yaqing ZHANG
- Publication Type:Journal Article
- Keywords:
Dental matrix protein 1;
Dental caries;
Immunohistochemistry;
Image analysis system
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of dental matrix protein 1(DMP1)in carious human permanent teeth and its possible role during the reparative process after pulp injury.Methods:10 of noncarious third molars (NC),10 of shallow carious (SC),10 of intermediate carious (IC) and 10 of deep carious (DC) were prepared for the detection of DMP1 in odontoblasts by immunohistochemical staining. DMP1 expression in odontoblasts was analyzed by image analysis system and expressed as integral optical density (IOD).Results:DMP1 was majorly detected in cytoplasms and processes of odontoblasts and odontoblast-like cells.The IOD values in the groups of NC,SC,IC and DC were 0.265?0.018,0.309?0.021,0.678?0.031 * and 0.691? 0.033 * respectively;that in the reparative dentin in DC group was 0.856?0.045 ** ( *vs NC P
