Expression of IL-6 in indirectly injured pulpal tissue from firearm wound in dog
- VernacularTitle:颌面部火器伤间接损伤牙髓组织中IL-6的免疫组化表达
- Author:
Jun LIU
;
Wensheng QI
;
Lan LIU
- Publication Type:Journal Article
- Keywords:
Maxillofacial injuries;
Firearm wound;
Dental pulp;
IL-6;
Immunohistochemistry
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the role of IL-6 in the dental pulp indirect injury by gunshot. Methods: The mandible was wounded by gunshot at (961.18?8.94) m/s in 17 dogs.2 h,6 h,1 d,3 d,7 d after injury molars,caspids,and lateral incisors were sampled respectively for IL-6 detection by immunohistochemical method in dental pulp. Results: The results showed that positive staining of IL-6 was observed predominantly in infiltrating inflammatory cells, vascular endothelial cells and some fibroblasts,IL-6 expression was consistent with the recruitment and activation of inflammatory cells, and with the severity duration of pulpal tissue injury and response. IL-6 level was increased in the dental pulp 6 h～3 d after injury.Conclusion: IL-6 is involved in regulating physiologic responses of dental pulp injuries in maxillofacial trauma by a projectile.
