Effects of Prevotella intermedia lipopolysaccharide on the gene expression in periodontal ligment cells
- VernacularTitle:中间普氏菌内毒素刺激前后下调人牙周膜细胞表达基因的研究
- Author:
Xianhua ZHANG
;
Bin ZHANG
;
Zhongliang ZHAO
- Publication Type:Journal Article
- Keywords:
Prevotella intermedia;
Lipopolysaccharides, Gene chip;
Periodontal ligament cells
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the gene expression in periodontal ligament cells (PDLCs) stimulated by Prevotella intermedia(Pi) lipopolysaccharide (LPS). Methods:PDLCs of passage 7 were treated with Pi LPS at 100 ?g/ml for 24 h, then gene express of the cells was examined by a gene chip of 512 genes. Results: Genes of Z46973,M62810,AF109632,U45879,X81882,M10051,D14520 and L36529 were downregulated.Conclusion:Some genes in PDLCs can be downregulated by Pi LPS.
