Restoration of radii defects with HAB/DBP composite in rabbits
- VernacularTitle:HAB/DBP复合物修复骨缺损的实验研究
- Author:
Feng LIU
;
Lihui TANG
;
Junzheng WU
- Publication Type:Journal Article
- Keywords:
Hydroxyapatite;
Bone defect;
Artificial bone;
Demineralized bone
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: The purpose of this study is to investigatc the effects of the HAB/DBP composite in the restoration of restoring bone defects. Methods: The HAB/DBP composiite, HAB or DMB samples were grafted into the defects of rabbit's radii respectively and the samples were examined 2 weeks, 4 weeks, 8 weeks and 12 weeks after operation with general, radiological and histological observations respectively.Results: In the group of HAB/DBP composssite implanted area , mesenchymal cells and new bone stromas were observed assembling 2 weeks after the operation. New bone formation and bone trabeculation were found 4 weeks after transplantation. A lot of bone trabeculation and composite degrad ation were observed 8 weeks after operation. The defects were completely restored 12 weeks after the surgery.Conclusion: The HAB/DBP composite has the properties of osteoconduction and osteoinduction, and its osteogenic ability is similar to that of DMB.
