The significance of Fas and FasL expression in pulpitis
- VernacularTitle:Fas/FasL在牙髓炎症过程中的分布及意义
- Author:
Qing YU
;
Buling WU
;
Mingzhen XIAO
;
Ning WANG
- Publication Type:Journal Article
- Keywords:
Gene expression;
Pulpitis;
Hybridlzation in sita;
Apoptosis
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the role of Fas/FasL signal in pulpitis. Methods: The expression of Fas/FasL in rat normal and inflammatory dental pulp was observed by immunohistochemical method and the expression of fas mRNA was studied by in situ hybridization. Results: A few of Fas and few of FasL positive cells were observed in normal dental pulp, while in inflammatory dental pulp many polymorphonuelear neutrophyl leukocytes(PMNs) and some pulp cells in the inflammatory area were stained positive. Conclusion: The apoptosis in dental pulp induced by Fas/FasL may play a role in pulpitis.