Application of egg-yolk-antibody to prevent recolonization of Streptococcus mutans
- VernacularTitle:利用鸡蛋抗体防止变形链球菌的再生
- Author:
Jianwu ZHOU
;
Huilong WANG
;
Zhonglai WANG
;
Pingfan RAO
- Publication Type:Journal Article
- Keywords:
Dental caries;
Streptococcus mutans;
Recolonization;
Bacterial antibodies;
Egg yolk antibody;
water soluble protein fraction
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of local application of the water soluble protein fraction,containing specific egg yolk antibody,on the recolonization of Streptococcus mutans.Methods:Whole cells of inactivated streptococcus mutans were used as antigen to immunize bens,then water soluble protein fraction(WSF) was extracted from the eggs. Mouth wash containing 0.1 mg/ml of WSF was prepared and administered to 8 volunteers.The mouth wash was used once every two days for 2 weeks.Vehicle solution was used in other 6 volunteers as the control.S.mutans in saliva was monitored for 100 days.Results:Before using the mouth washes,S.mutans level in saliva of the volunteers was 36.4%.S.mutans was removed by hibitane,it kept less than 3% in 100 days in the tested individuals,while 23%～37% in the controls.Conclusion:The WSF containing specific egg yolk antibody can effectively prevent the recolonization of streptococcus mutans.
