Adhesive peptide RGD promotes the attachment and spreading of rat osteoblasts
- VernacularTitle:粘附肽精氨酸-甘氨酸-天冬氨酸促进小鼠成骨细胞在材料表面的附着和铺展
- Author:
Hui HUANG
;
Xuanxiang MA
;
Guanghui ZHU
;
Hui ZHANG
;
Ye YUE
- Publication Type:Journal Article
- Keywords:
Arginlie;
Glycine;
Aspartic acid;
Cell adhesion
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of adhesive peptide arginlie-glycine-aspartic acid(RGD) on the attachment and spreading of osteoblast on the surface of dental implant materials. Methods: RGDC peptides were covalently immobilized on the surface of dental implant materials by SAMs. Rat osteoblasts were isolated and cultured on the materials. The attachment and spreading behavior of the cells were analyzed by cell counting and FITC-conjugated immunofluorsescent assay. Results: On the RGD coated surface, cell attachment was increased by 50% (P
