PAI-1 protein level in oral and maxillofacial tumors
- VernacularTitle:PAⅠ-1蛋白水平在口腔颌面部肿瘤中的研究
- Author:
Zizhong WU
;
Rongfa BU
;
Yunlian LI
- Publication Type:Journal Article
- Keywords:
Plasminogen inactivators;
Mouth;
Jaw;
Face;
Neoplasms
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
砄bjective:To investigate the expression of plasminogen activator inhibitor 1(PAI 1) in oral and maxillofacial tumors and the relationship between PAI 1 and pathological parameters.Methods:Chromogenic substrate assay was used to determine PAI 1 level in tumor tissues and ELISA was used to detect the concentration of PAI 1 in tissue extracts in 30 cases of malignant tumors and 10 of benign tumors in oral and maxillofacial area.Results:Higher level and concentration of PAI 1 were found in malignant tumors than in tumor adjacent tissues or benign tumors ( P
