A Progress on the Effects of Resveratrol on Tumor Cells

VernacularTitle:白藜芦醇诱导肿瘤细胞凋亡研究进展
Author: Junjun HAN ; Yuming ZHANG ; Xuefeng PAN ; Song XIE ; Fei DUAN ; Hongquan LI
Keywords: Resveratrol; tumor; antioxidation; polyphenols; apoptosis
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2016;18(12):2176-2181
CountryChina
Language:Chinese
Abstract: Resveratrol is a natural polyphenolic substance with a variety of bioactivities,such as anti-oxidation,anti-tumor and apoptosis induction.This paper summarized the recent research progress of resveratrol induced cancerous cell apoptosis,including human cervical cancer HeLa cells,leukemia cells,hepatoma cells and gastric cancer cells,and analyzed the molecular mechanism behind resveratrol-induced cell apoptosis in tumor.In addition,resveratrol was investigated by blocking the cell cycle,regulating the expressions of related genes and proteins and mitochondria-induced apoptosis pathways as a potential application of cancer drugs to clinical researches.