Risk factors for hyperamylasemia after endoscopic retrograde cholangiopancreatography
10.3969/j.issn.1001-5256.2016.01.022
- VernacularTitle:经内镜逆行胰胆管造影术后高淀粉酶血症的危险因素分析
- Author:
Aishan YIERPAN
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
hyperamylasemia;
pancreatitis;
cholangiopancreatgraphy,endoscopic retrograde;
risk factors
- From:
Journal of Clinical Hepatology
2016;32(1):119-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toinvestigatetheriskfactorsforthedevelopmentofpost-endoscopicretrogradecholangiopancreatographypancrea-titisandhyperamylasemia(PEPH)afterendoscopicretrogradecholangiopancreatography(ERCP).Methods Theclinicaldataof233pa-tients who underwent therapeutic ERCP from January 2012 to December 2014 in our hospital and met the inclusion criteria were analyzed ret-rospectively.Basic information including age,sex,drinking history,single stone,triglyceride,and nationality was extracted,and detailed information on intraoperative procedure,intraoperative diagnosis,and complications for ERCP was carefully recorded.Chi-square test was applied for comparison of categorical data between groups,and Logistic regression analysis were applied to determine the risk factors for the developmentofPEPH.Results TheincidenceofPEPHwas26.6%(62/233).Univariateanalysisshowedthatfemalesex(χ2=3.320, P=0.045),drinking history (χ2 =6.108,P=0.010),common bile duct stenosis (χ2 =5.767,P=0.012),single stone (χ2 =9.121, P=0.020),juxta-ampullary duodenal diverticula (χ2 =28.170,P<0.001),and abnormal triglyceride (χ2 =54.717,P<0.001) might be the risk factors for PEPH,and these factors differed significantly between the two groups.Multivariate analysis showed that female sex (OR=1.616,P=0.025)drinking history (OR=2.360,P=0.010),common bile duct stenosis (OR=2.163,P=0.012),juxta-ampullary duodenal diverticula (OR=5.502,P<0.001),and abnormal triglyceride (OR=12.924,P<0.001)were independent risk fac-torsforPEPH.Conclusion Femalesex,drinkinghistory,commonbileductstenosis,juxta-ampullaryduodenaldiverticula,andabnor-mal triglyceride are independent risk factors for PEPH,and targeted preventive measures for such high-risk populations can effectively re-duce the incidence of PEPH.
