The impact on risky decision-making in patients with insular glioma
10.3760/cma.j.issn.1674-6554.2016.04.007
- VernacularTitle:岛叶胶质瘤对风险决策认知功能的影响
- Author:
Guangming WANG
;
Chaoshi NIU
;
Peng CHEN
- Publication Type:Journal Article
- Keywords:
Insular;
Glioma;
Decision-making;
Cognitive function
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2016;25(4):319-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of focal insular glioma on risky decision-making and to verify the causal relationship between insular and risky decision-making cognitive process.Methods 12 patients with focal insular glioma,15 healthy individuals and 15 lesion controls with brain glioma predominantly affecting non-insular lobes were tested with a risky decision-making task.The results were compared by statistical methods.Results The bet time (BT),report time (RT) and bet or report failure (F) of insular glioma patients were (1.61±0.06) s,(1.61±0.10) s and (2(2,3.75)) respectively.BT,RT and F of lesion controls were (0.70±0.11) s,(0.69±0.11s) and (0(0,0)) respectively and those of healthy group were (0.71 ±0.10) s,(0.68 ±0.11) s and (0(0,1)) respectively.Compared with normal subjects and lesion controls,BT and RT of insular glioma patients were significantly extended,and F was observably increased (P＜0.01).BT,RT and F of lesion controls had no significant difference compared with those of healthy group (P＞0.05).Conclusion The risky decision-making cognitive process may be influenced by insular glioma.The insular region plays a necessary role in decision-making under risk and insular causally is involved in risky decision making.
