Study of in vitro Percutaneous Permeability of Quercetin in Ginkgo Biloba Extract
- VernacularTitle:银杏叶提取物中槲皮素体外经皮渗透的研究
- Author:
Xiaoxuan ZENG
;
Guizhi ZHANG
;
Yimei LIU
;
Keli CHEN
- Publication Type:Journal Article
- Keywords:
Ginkgo Biloba extract;
Quercetin;
Percutaneous permeability
- From:
China Pharmacist
2015;18(12):2033-2035
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the percutaneous permeability of quercetin in Ginkgo Biloba extract in vitro. Methods: Ginkgo Biloba extract was dissolved in 50% ethanol. The percutaneous permeability experiment through mouse skin was conducted using a modified Franz diffusion cell. The penetration amount of quercetin was determined by HPLC. Results:The percutaneous permeability of quercetin in the solution was approximately characterized by zero-order kinetics. Conclusion:Quercetin in Ginkgo Biloba extract can be absorbed through skin.