Specific Chromatogram of Fufang Shexiang Injection and Simultaneous Determination of Five Components by GC
- VernacularTitle:复方麝香注射液特征图谱及5种主要成分的含量测定
- Author:
Yongli LIU
;
Hao YUAN
;
Dongmei LI
;
Xiaolian NIU
;
Li FENG
- Publication Type:Journal Article
- Keywords:
Fufang Shexiang injection;
GC;
Specific chromatogram;
Determination;
Volatile components
- From:
China Pharmacist
2015;18(12):2036-2038
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the specific chromatogram of Fufang Shexiang injection and simultaneously determine five com-ponents( menthol,borneol,patchouli alcohol,muscone,α-asarone) in the injection by GC. Methods:The sample solution was extracted by a solid-phase extraction method. The separation was performed on a DB-WAX GC capillary column with an FID detection. Results:The specific chromatogram had six common peaks, and the similarity was above 0. 91. The five chemical components(menthol,borne-ol,patchouli alcohol,muscone,α-asarone) were well separated and with good linear relationship, the recoveries were between 95. 1 and 102. 6%, and RSD was less than 3. 0%. Conclusion:The method is simple, accurate and reproducible. The specific chromatogram combined with multi-component determination can reflect the overall quality of Fufang Shexiang injection, which can be used for the quality control of the preparation.
