Effect of Amlodipine Atorvastatin Tablets on Blood Pressure and Blood Lipid of Patients with Hypertension Complicated with Coronary Heart Disease
- VernacularTitle:氨氯地平阿托伐他汀对高血压合并冠心病患者血压、血脂的影响观察
- Author:
Airong ZHANG
;
Xiao WU
;
Liangyuan WU
- Publication Type:Journal Article
- Keywords:
Amlodipine atorvastatin tablets;
High blood pressure;
Coronary heart disease;
Blood pressure;
Blood fat
- From:
China Pharmacist
2015;18(12):2095-2097
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of amlodipine atorvastatin on blood pressure and blood lipid in the patients with hy-pertension complicated with coronary heart disease (CHD). Methods: Totally 80 cases of outpatients with hypertension complicated with CHD were randomly divided into the observation group (40 cases) and the control group (40 cases). The control group was given amlodipine 10 mg,po,qn, and the observation group was given amlodipine and atorvastatin tablets 20 mg,po,gn, and the treatment course was 6 weeks. The changes of blood pressure and blood lipid in the two groups before and after the treatment were observed, and the clinical curative effect and adverse reactions were also studied. Results:Compared with those before the treatment, systolic blood pressure, diastolic blood pressure and blood fat in the two groups were all improved after the treatment, and the difference was statisti-cally significant (P<0.05), and the improvement in the observation group was more notable than that in the control group (P <0. 05). The total effective rate of the observation group was 92. 5%, which was higher than that in the control group(80. 0%, P<0. 05). The incidence of adverse reactions between the two groups showed no significant difference (P>0. 05). Conclusion: Amlo-dipine atorvastatin tablets can significantly improve blood pressure and blood lipid in the patients with hypertension complicated with CHD with promising clinical curative effect and few side effects, which is worthy of wide use in clinics.
