Pharmaceutical Care for Drug-induced Liver Injury
- VernacularTitle:药物性肝损伤的临床药学监护
- Author:
Xin HE
;
Lihua LIU
;
Honglin MA
;
Li ZHANG
;
Xin LI
;
Mingxiang ZHANG
- Publication Type:Journal Article
- Keywords:
Drug-induced Liver Injury;
Clinical pharmacist;
Pharmaceutical Care
- From:
China Pharmacist
2015;18(12):2107-2109
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the pharmaceutical care methods for the patients with drug-induced liver injury. Methods:The participation process of clinical pharmacists in 3 cases of typical drug-induced liver injury was with detailed introduction and analy-sis in the paper. Results:The case 1 indicated that new drugs probably with drug-induced liver injury should be warned in the process of clinical medication. The case 2 suggested that TDM, as a useful assessment weapon, could be fully used to find the source medi-cines when drug-induced liver injury occurred. The case 3 showed the specific cases, especially the patients with abnormal liver func-tion, should be focused on, the medicines with high liver toxicity should be avoided and the medicines with mild liver toxicity could be chosen. Conclusion:Clinical pharmacists should participate in the clinical practice of drug-induced liver injury with multi-channel and multi-link, and pay attention to the drugs with high risk of liver injury. Meanwhile, clinical pharmacists should perform TDM monito-ring to provide positive evidence for the diagnosis of drug-induced liver injury, and focus on the liver and kidney functions to provide better pharmaceutical care for the patients.
