Quality Control of Shuangshengen Capsules
- VernacularTitle:双参根胶囊的质量控制
- Author:
Tiequan CAI
;
Yuanyuan HE
;
Xinyuan LI
;
Chunfu LI
;
Xueqiong ZHANG
- Publication Type:Journal Article
- Keywords:
TLC;
Shuangshengen capsules;
Panax ginseng;
Salvia miltiorrhiza;
Radix pueraria;
HPLC
- From:
China Pharmacist
2015;18(12):2190-2193
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a quality control method for Shuangshengen capsules ( Salvia miltiorrhiza, Panax ginseng and Radix pueraria) . Methods:TLC was performed to identify Salvia miltiorrhiza, Panax ginseng and Radix pueraria. HPLC was used to determine the contents of puerarin and ginsenoside Rg1 . Results:The spots obtained from the test solutions had the same color as the reference solution at the same position. The spots on the TLC plates were clear without any interference. The calibration curve was line-ar within the range of 14. 42-115. 36 ng for puerarin, and the average recovery was 99. 94%(RSD=0. 13%, n=5). The calibration curve was linear within the range of 0. 1-0. 8 μg for ginsenoside Rg1, and the average recovery was 99. 85%(RSD=0. 42%,n=5). Conclusion:The method is reliable, simple and reproducible, and suitable for the quality control of Shuangshengen capsules.
