Content Comparison of Taxol in Different Parts of Taxus Madia and Taxus Chinensis var. Mairei
- VernacularTitle:曼地亚红豆杉与南方红豆杉不同部位中紫杉醇含量比较研究
- Author:
Guangyi YANG
;
Fang YE
;
Li LI
;
Chenning ZHANG
;
Jinbao WEI
;
Pei HU
- Publication Type:Journal Article
- Keywords:
Taxol;
Taxus madia;
Taxus chinensis var. mairei;
Content
- From:
China Pharmacist
2015;(11):1844-1847
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the taxol content in different parts of Taxus madia and Taxus chinensis var. mairei to provide reference for the future researches. Methods:The active ingredients were extracted by a mixed solvent (50% acetone and 50% ethyl acetate) , the target compound taxol was separated by a neutral Al2 O3 solid phase column, and then the taxol content was analyzed and compared among the different parts of Taxus madia and Taxus chinensis var. mairei by HPLC. Results:Taxol in velamen of Taxus ma-dia had the highest content among all the samples, which was 0. 0439% and 88 times as high as that in the bark of Taxus chinensis var. mairei. Conclusion:Among all the samples of Taxus madia and Taxus chinensis var. mairei, velamen of Taxus madia has the highest taxol content.
