Determination of Substances with High Molecular Weight in Porcine Anterior Pituitary and Adrenal Cortex Extracts Injection
- VernacularTitle:垂体前叶肾上腺皮质提取物注射液中高分子物质测定
- Author:
Jianghong GUO
;
Hao ZENG
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
Porcine anterior pituitary and adrenal cortex extracts injection;
Substances with high molecular weight;
Determina-tion
- From:
China Pharmacist
2015;18(10):1666-1668
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determinate the substances with high molecular weight in porcine anterior pituitary and adrenal cortex extracts injection. Methods:The HPLC analysis was performed on a TSK-GEL G2000SWXL(7. 8 mm × 300 mm,5 μm) column with the mobile phase of trifluoroacetic acid-acetonitrile-water(0. 05:35:65). The flow rate was 0. 5 ml·min-1, and the detection wave-length was 214 nm. Results:The substances with high molecular weight in porcine anterior pituitary and adrenal cortex extracts injec-tion was below 1%. Conclusion:The method is simple and repeatable, which can be used for the control of the substances with high molecular weight in porcine anterior pituitary and adrenal cortex extracts injection.
