Determination of Si Migration in Penehyclidine Hydrochloride Injection Packed with Low Borosilicate Glass Ampoule
- VernacularTitle:低硼硅玻璃安瓿包装盐酸戊乙奎醚注射液中硅迁移量的测定
- Author:
Zongying XU
;
Xinglan LIU
;
Peining LIAO
- Publication Type:Journal Article
- Keywords:
Low borosilicate glass ampoule;
Penehyclidine hydrochloride injection;
Si;
Migration
- From:
China Pharmacist
2015;18(10):1693-1694
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of Si migration in penehyclidine hydrochloride injection packed with low borosilicate glass ampoule. Methods: Si migration was determined by graphite furnace-atomic absorption spectrometry. Re-sults:The linear concentration range was 0-85 ng·ml-1(r=0. 995 6). The average recovery was 95. 85% and RSD was 4. 60% (n=9). Conclusion:The method is sensitive, rapid and accurate with good repeatability, which can be used to determine Si migration in penehyclidine hydrochloride injection packed with low borosilicate glass ampoule.
