Six Cases of Anaphylactic Shock Induced by Alprostadil Injection
- VernacularTitle:前列地尔注射液致过敏性休克6例
- Author:
Yin LIU
;
Yun YANG
;
Mengmeng YING
;
Chunping MIAO
;
Yaodong YAN
- Publication Type:Journal Article
- Keywords:
Alprostadil injection;
Anaphylactic shock
- From:
China Pharmacist
2015;18(10):1771-1773
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the feature of anaphylactic shock induced by alprostadil injection. Methods: Totally 1624 pa-tients treated with alprostadil injection in our hospital from January to March 2014 were undergone adverse drug reaction monitoring. Six cases of anaphylactic shock induced by alprostadil injection were statistically analyzed. Results:6 cases of anaphylactic shock induced by alprostadil injection occurred in the department of intervention and most of thd reaction happened in arterial injection. Two lot num-ber of drugs were in high frequency. Patients showed a sharp fall in blood pressure, chest discomfor, palpitation, shortness of breath, paleness, sweating and other symptoms. After anti allergy, blood pressure, oxygen the rapy and other treatment measures vital signs gradully stabilized. Conclusion:Anaphylactic shock induced by alprostadil injection is in correlation with the administration mode of artery injection. The change of the patient' s condition and vital signs should be closely observed when we inject the patient with alpros-tadil injection. We must prevent the occurrence of serious adverse reactions.
