Clinical Effect Observation of Alendronate Combined with Jintiange Capsules in the Treatment of Postm-enopausal Osteoporosis
- VernacularTitle:阿仑磷酸钠联合金天格胶囊治疗绝经后骨质疏松临床观察
- Author:
De CAI
;
Zhixiu LIN
;
Zhihua HUANG
;
Hao LIN
;
Qun LUO
- Publication Type:Journal Article
- Keywords:
Alendronate;
Jintiange capsules;
Postmenopausal osteoporosis;
Clinical effect
- From:
China Pharmacist
2015;(8):1352-1354
- CountryChina
- Language:Chinese
-
Abstract:
To explore the clinical effect of alendronate combined with Jintiange capsules in the treatment of postmeno-pausal osteoporosis ( PMOP) . Methods:Ninety-eight cases of PMOP patients were randomly divided into three groups. The combina-tion treatment group (34 cases) was treated with alendronate tablets combined with Jintiange capsules, while the control group A (32 cases) and the control group B (32 cases) was respectively treated with alendronate tablets and Jintiange capsules, and the treatment course was six months. The changes of the clinical symptom score, bone mineral density ( BMD) , serum calcium, serum phosphorus, AKP, hepatorenal function and so on before and after the treatment were recorded. Results:After the six-month treatment, the clinical symptom score of the treatment group was much better than that in the two control groups(P<0. 05). BMD in the three groups was in-creased after the treatment(P<0. 05), and the increase in the treatment group was more notable than that in the two control groups(P<0. 05). Conclusion:Alendronate combined with Jintiange capsules can effectively improve BMD and relieve clinical symptoms in the patients with PMOP, which is worthy of promoted application.
