Pharmacodynamics Studies of Yinyanjing Gel in the Treatement of Bacterial Vaginitis in Rats
- VernacularTitle:阴炎净凝胶对大鼠细菌性阴道炎的药效学研究
- Author:
Zishan LI
;
Rongrong WANG
;
Ruilian LI
;
Yali WU
- Publication Type:Journal Article
- Keywords:
Yinyanjing gel;
Rats;
Bacterial vaginitis
- From:
China Pharmacist
2015;(8):1389-1391
- CountryChina
- Language:Chinese
-
Abstract:
To study the bacteriostat, anti-inflammatory and relieving itching effects of Yinyanjing gel. Methods: A double dilution method was used to detect the in vitro bacteriostat effect of Yinyanjing gel. The therapeutic effects of Yinyanjing gel on bacterial vaginitis were observed in rats. The antipruritic effect of Yinyanjing gel was observed in guinea pigs. Results:MIC for Staphy-lococcus aureus was 47. 39 mg·ml-1 , and that for Escherichia coli was 189. 59 mg·ml-1 . The therapeutic effects of Yinyanjing gel on bacterial vaginitis were significant. Yinyanjing gel showed notable antipruritic effect on the itching induced by histamine phosphate in guinea pigs. Conclusion:Yinyanjing gel exhibits significant effects of bactriostasis,anti-inflammation and relieving itching.
