Optimization of Water Extraction Process for Jinyin Lidan Oral Liquids by Orthogonal Experiment
- VernacularTitle:正交试验法优选金茵利胆口服液水提工艺
- Author:
Xinbo PAN
;
Caidong LI
;
Xin WANG
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
Jinyin Lidan oral liquids;
Orthogonal test;
Water extraction;
Chlorogenic acid;
üarigin;
üeohesperidin
- From:
China Pharmacist
2015;(4):585-588
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the optimal water extraction process of Jinyin Lidan oral liquids. Methods:An orthogonal de-sign was used in the extraction optimization using the yield and content of chlorogenic acid,narigin and neohesperidin as the evaluation indices and the volume of water,extraction times,extraction time and soaking time as the influencing factors. The contents of chloro-genic acid,narigin and neohesperidin were detected by HPLC to screen the best extraction technology. Results:The best water extrac-tion conditions were as follows:the amount of the added water was 8 times of the medicinal materials,the soaking time was 1 h,and the decoction was carried out twice with the duration of 1. 5 h for each. Conclusion:The process is stable and reasonable,which pro-vides research foundation for the production and quality control.
