Determination of Compound Sodium Acetate Injection
- VernacularTitle:复方醋酸钠注射液的含量测定
- Author:
Zhaohui DENG
;
Wenjun HU
;
Aihong LI
- Publication Type:Journal Article
- Keywords:
Compound sodium acetate injection;
Sodium chloride;
Calcium chloride;
Potassium chloride;
AAS
- From:
China Pharmacist
2015;(6):1038-1040
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To improve the determination method for compound sodium acetate injection. Methods:Atomic absorption spectrophotometry ( AAS) was used to determine sodium chloride, calcium chloride and potassium chloride in compound sodium acetate injection. Results:The linear range of calcium ion, potassium ion and sodium ion was 9.124 ×10 -7-1.369 ×10 -5 g·ml-1(r =0.999 5),1.501 ×10 -7 ~4.504 ×10 -6 g·ml-1(r=0.999 2) and 7.500 ×10 -8-2.251 ×10 -6 g·ml-1(r=0.999 5), and the av-erage recovery was 100. 4%(RSD=1. 4%,n=9),102. 4%(RSD=1. 6%,n=9) and 100. 3% (RSD=1. 1%,n=9), respectively. Conclusion:The method is simple, accurate and reproducible, and can be used to control the quality of compound sodium acetate in-jection.
