Research Progress in Polyethylene Glycol Modified Chitosan Applied in Biomedical Field
- VernacularTitle:聚乙二醇修饰壳聚糖在生物医学领域的研究进展
- Author:
Xindu YANG
;
Qiqing ZHANG
- Publication Type:Journal Article
- Keywords:
Chitosan;
Polyethylene glycol;
Research progress
- From:
China Pharmacist
2015;(6):1014-1016
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide reference for the intensive study on polyethylene glycol modified chitosan. Methods:The relat-ed literatures at home and abroad were looked up and retrieved from 2004 to 2014, and the related contents were summarized. Results:The methods for the preparation of polyethylene glycol modified chitosan were various. Polyethylene glycol modified chitosan could be used as the carrier for nano-drug and gene therapy, the base of temperature-sensitive hydrogel, polymeric prodrug and the repair mate-rial of tissue engineering. Conclusion:Polyethylene glycol modified chitosan can be wildely used in biomedical field. However, the re-lated research is only in vitro. The in vivo studies should be further systematic and intensive.