Study on Diterpenoid Alkaloids from the Roots of Aconitum Straminiflorum
- VernacularTitle:草黄乌头二萜生物碱成分研究
- Author:
Fei YE
;
Guiqiong LI
;
Shuhui ZI
;
Limei ZHANG
;
Yanping CHEN
;
Qianran LI
- Publication Type:Journal Article
- Keywords:
Aconitum straminiflorum;
Ranunculaceae;
Diterpenoid alkaloids
- From:
China Pharmacist
2015;(4):538-540
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the chemical constituents of Aconitum straminiflorum. Methods:The air-dried roots of A. stra-miniflorum were powdered and extracted three times with 90% ethonal under reflux. After the removal of the solvent under reduced pressure,the crude extract was dissolved in 1. 5% HCl solution(7 L). The acidic solution was basified to pH 9. 0 with ammonia (25%)and extracted with CHCl3 to obtain crude extract of total alkaloids after the removal of CHCl3 . The compounds were isolated and purified by column chromatography and identified based on spectral analysis( MS,1 H-üMR and 13 C-üMR). Results:Totally 7 compounds were isolated from A. straminiflorum,and characterized as aconosine(1),13-deoxyludaconitine(2),dolaconine(3), ezochasmanine(4),talatisamine(5),scopaline(6)and cammaconine(7),respectively. Conclusion:Seven diterpenoid alkaloids are isolated from A. Straminiflorum for the first time.
