Effect Evaluation of Continuing Intervention on Prophylactic Application of Antibiotics in Sterile Operation in Urology Department by Clinical Pharmacist
- VernacularTitle:临床药师持续干预泌尿外科清洁手术预防用抗菌药合理使用的效果评价
- Author:
Airong YU
;
Xing FAN
;
Dan SU
;
Yan ZHAO
;
Huawen XIN
- Publication Type:Journal Article
- Keywords:
Clinical pharmacist;
Department of urology;
Sterile operation;
Prophylactic antibiotics;
Intervention
- From:
China Pharmacist
2015;(6):970-972
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of continuing intervention on prophylactic application of antibiotics in sterile operation in urology department by clinical pharmacist to provide reference for the clinical prophylactic application of antibiotics. Methods:All cases of discharged patients underwent sterile operation in urology department of our hospital from July 2010 to June 2014 were divided into three groups according to the intervention time and methods: non-intervention group(n=141), stage Ⅰ intervention group(n=139), stage Ⅱ intervention group (n=162) and stage Ⅲ intervention group (n=137). The prophylactic application of antibiotics was statistically analyzed. Results:After the continuing intervention, the prophylactic application rate of antibiotics in the three inter-vention groups was decreased significantly from 100% before the intervention respectively to 34. 5%,18. 5% and 14. 6% after the in-tervention (P<0. 01). The rationality rate of prophylactic application was improved significantly from 36. 9% before the intervention respectively to 58. 3%, 63. 3% and 85. 0% after the intervention (P<0. 01). The course of prophylactic application was decreased significantly from (138.2 ±31.6)h respectively to (89.9 ±48.0)h,(72.8 ±32.5)h and(45.1 ±29.5)h (P<0.01) and the post-operative infection rate was decreased from 2. 8% respectively to 2. 1%,1. 8% and 1. 4%. Conclusion:The pharmaceutical interven-tion is feasible and valid to improve the rational prophylactic use of antibiotics in urological surgery.
