Efficacy and Immunoregulation of Pidotimod Combined with Routine Therapy in Children with Recurrent Respiratory Tract Infections
- VernacularTitle:匹多莫德联合常规治疗措施治疗反复呼吸道感染患儿疗效及免疫调节作用观察
- Author:
Xiaohong HU
;
Hui PAN
;
Xianli JI
- Publication Type:Journal Article
- Keywords:
Recurrent respiratory tract infections;
Pidotimod;
Children;
Immunological function
- From:
China Pharmacist
2015;(5):799-801
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the efficacy and immunoregulation of pidotimod combined with routine treatment in the children with recurrent respiratory tract infections. Methods:Totally 114 cases of children with recurrent respiratory tract infections were divid-ed into the control group and the treatment group according to the sequence of hospitalization. The 58 patients in the control group re-ceived the conventional treatment, while the 56 patients in the treatment group were given pidotimod additionally. After two-month treatment, all the children were given 1 -6-month follow-up, and the symptom disappearance time, clinical efficacy, recurrence, physiological indices and change of immunological function in the two groups were observed and compared. Results:The disappearance time of symptom and lung physical signs in the observation group was much shorter than that in the control group (P<0. 05);the total effective rate of the observation group was 92. 86%, which was significantly higher than that of the control group (67. 24%, P <0. 001). The number of upper and lower respiratory tract infections in the observation group was significantly lower than that in the con-trol group (P<0. 05). After the treatment, the immune parameters in the observation group were significantly improved (P<0. 01), which were significantly higher than those in the control group (P<0. 05 or P<0. 01). The immune parameters before and after the treatment in the control group showed no statistically significant difference (P>0. 05). Conclusion:Pidotimod combined with routine treatment in the children with recurrent respiratory tract infections exhibits promising efficacy, which can improve immunity effectively.
