Alcohol Concentration Optimization for Jinyin Qingre Oral Liquids Extracted by Semi-bionic Extraction (SBE)
- VernacularTitle:金茵清热口服液半仿生提取醇沉浓度优选
- Author:
Fang YE
;
Li LI
;
Guangyi YANG
;
Liangyong HUANG
;
Chenning ZHANG
;
Jingbao WEI
- Publication Type:Journal Article
- Keywords:
Jinyin Qingre oral liquids;
Semi-bionic extraction;
Alcohol concentration;
Comprehensive evaluation
- From:
China Pharmacist
2015;(5):766-769
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the alcohol concentration for Jinyin Qingre oral liquids extracted by semi-bionic extraction (SBE). Methods:Using proportional division method to set up 5 alcohol concentration 30%,55%,61. 25%,67. 5%,80% for the ex-periment . The dried extract yield and the contents of chlorogenic acid ,geniposide,salviandic acid B and total phenolic acid were set up as indexes which were standardized as the comprehensive evaluation value ( Y) ,using the weighting coefficient had been set. Choosing the appropriate concentration by comparing the value of Y. Results:The order of comprehensive evaluation value was as follows:30%>61. 25% >55% >80% >67. 5%. Conclusion:Combining the clarity of the oral liquids, the best alcohol concentration in SBE for Jinyin Qingre oral liquids is 61. 25%.