Study Advances in Synergism and Detoxication of Drug Combination with Cisplatin in Chemotherapy
- VernacularTitle:顺铂化疗联合用药的增效减毒作用研究进展
- Author:
Hong YANG
;
Can GONG
;
Changhong WANG
;
Cong QI
- Publication Type:Journal Article
- Keywords:
Cisplatin;
Toxicity;
Drug combination;
Synergism and detoxication
- From:
China Pharmacist
2015;(5):836-840
- CountryChina
- Language:Chinese
-
Abstract:
Cisplatin is effective in the treatment of various solid tumors. However, its clinical application is limited because of the severe side-effects such as nephrotoxicity, hepatotoxicity, ototoxicity and so on. Drug combination is advocated in clinics for synergism and detoxication. In order to provide some referencs for the research of drug combination and clinical treatment regimen, the research advances in the synergism and detoxication of drug combination of cisplatin with chemicals/ traditional Chinese medicines in recent years are reviewed in the paper.
