Extraction Technology for Antitumor Active Components in Fructus Ligustri Lucidi
- VernacularTitle:女贞子抗肿瘤活性成分提取工艺考察
- Author:
Nana ZHANG
;
Zhenwei ZHANG
;
Lei SHI
- Publication Type:Journal Article
- Keywords:
Fructus ligustri lucidi;
Luteolin;
Pelargidenon;
D-optimal design
- From:
China Pharmacist
2015;(2):215-219
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction process of antitumor active ingredients in fructus ligustri lucidi. Methods:Using fructus ligustri lucidi medicinal herb as the raw material, the extraction process of luteolin and pelargidenon in the herb was screened by D-optimal design. The extraction yield of different extraction processes was compared to obtain the optimal extraction conditions. Re-sults:The best extraction conditions were as follows:adding 12-fold 95% ethanol, extracting 2 times with 60 minutes for each time. Conclusion:The optimal extraction technology can provide significant reference for the further pharmacodynamic effect development of fructus ligustri lucidi.