Quantitative and Qualitative Determination of Impurities in Lansoprazole for Injection
- VernacularTitle:注射用兰索拉唑杂质定量测定及定性研究
- Author:
Lin PENG
;
Yanming LIU
;
Haiyan LONG
;
Bin LIAO
- Publication Type:Journal Article
- Keywords:
Lansoprazole for injection;
Impurities;
Quantitative;
Qualitative
- From:
China Pharmacist
2015;(2):319-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the method for determining the related substances in lansoprazole for injection and qualitatively study the impurities. Methods:An HPLC method and an HPLC-MS method were used with isocratic elution and DAD as the detector. Results:The priciple impurity in all samples was impurity B. Conclusion:The method is fast, simple and sensitive, and suitable for the determination of the related substances in lansoprazole for injection.
