Optimization of Semi-bionic Extraction Conditions for Jinyin Qingre Oral Liquids by Uniform Design
- VernacularTitle:均匀设计优选金茵清热口服液半仿生提取的工艺条件
- Author:
Fang YE
;
Xiangyan LIU
;
Guangyi YANG
;
Liangyong HUANG
;
Zegan LIU
;
Ting DU
- Publication Type:Journal Article
- Keywords:
Uniform design;
Jinyin Qingre oral liquids;
Semi-bionic extraction;
Extraction condition
- From:
China Pharmacist
2015;(2):205-208
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the conditions of semi-bionic extraction for Jinyin Qingre oral liquids. Methods:The best con-ditions of the semi-bionic extraction for Jinyin Qingre oral liquids was optimized by uniform design with the yield of chlorogenic acid, geniposide and total phenolic acid, and the dried extract weight as the indices in a comprehensive evaluation. Results:The optimal pH of water for the three-time decoction was 2. 89, 6. 50 and 8. 43, respectively, and the total extraction time was 2. 0 h. Conclusion:Combined with the actual production, the pH value of water is 3. 0, 6. 5 and 8. 5 with the decoction time of 1. 0, 0. 5 and 0. 5h, re-spectively.
